Journal article
Increased blood pressure responses to central angiotensin II in spontaneously hypertensive rats
Klinische Wochenschrift, Vol.56 Suppl 1(1), pp.47-49
1978
DOI: 10.1007/BF01477452
PMID: 732252
Abstract
The blood pressure responses following infusions of angiotensin II (ANG II) into the brain ventricles (i.v.t.) have been tested in spontaneously hypertensive (SH) rats and in normotensive Wistar Kyoto (WK) rats. The mean arterial blood pressure increases were significantly higher in SH rats than in WK rats. Propranolol treatment reduced blood pressure increases to i.v.t. ANG II in WK, but not in SH rats. The higher sensitivity to i.v.t. ANG II in SH rats supports a role of central ANG II in the maintenance of high blood pressure in SH rats.
Details
- Title: Subtitle
- Increased blood pressure responses to central angiotensin II in spontaneously hypertensive rats
- Creators
- A K JohnsonW SimonK SchazU GantenD GantenJ F Mann
- Resource Type
- Journal article
- Publication Details
- Klinische Wochenschrift, Vol.56 Suppl 1(1), pp.47-49
- DOI
- 10.1007/BF01477452
- PMID
- 732252
- ISSN
- 0023-2173
- eISSN
- 1432-1440
- Language
- English
- Date published
- 1978
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health and Human Physiology
- Record Identifier
- 9984213271902771
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