Journal article
Increased incidence of diabetes mellitus in relation to abdominal adiposity in older women
Journal of clinical epidemiology, Vol.44(3), pp.329-334
1991
DOI: 10.1016/0895-4356(91)90044-A
PMID: 1999691
Abstract
The relationship between body fat distribution, measured by the ratio of waist-to-hip circumferences (WHR), and the 2 year incidence of diabetes mellitus was examined in a cohort of 41,837 women aged 55–69 years.
The 399 women who reported the new onset of diabetes had a significantly greater mean body mass index (kg/m
2) and WHR than non-cases. After adjustment for body mass index (BMI), age and education level using multivariate logistic regression, WHR was a significant independent predictor of diabetes in a dose-response fashion. Cases were 4.6 times (95% CI = 3.8, 5.6) more likely than non-cases to be in the upper tertile of WHR and 2.2 times (95% CI = 1.8, 2.7) more likely to be in the middle tertile. Women in the highest tertiles of both WHR and BMI had a 14.4-fold (95% CI = 9.5, 21.9) higher risk of diabetes than women in the lowest tertiles. These results demonstrate that increased abdominal adiposity is a significant independent risk factor for the development of diabetes mellitus in older women.
Details
- Title: Subtitle
- Increased incidence of diabetes mellitus in relation to abdominal adiposity in older women
- Creators
- Susan A. Kaye - University of MinnesotaAaron R. Folsom - University of MinnesotaJ.Michael Sprafka - University of MinnesotaRonald J. Prineas - University of MiamiRobert B. Wallace - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of clinical epidemiology, Vol.44(3), pp.329-334
- DOI
- 10.1016/0895-4356(91)90044-A
- PMID
- 1999691
- NLM abbreviation
- J Clin Epidemiol
- ISSN
- 0895-4356
- eISSN
- 1878-5921
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1991
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984364431902771
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