Journal article
Increases in multimorbidity with weight class in the United States
Clinical obesity, Vol.11(3), pp.e12436-n/a
06/2021
DOI: 10.1111/cob.12436
PMCID: 8454494
PMID: 33372406
Abstract
Little is known regarding how multimorbidity combinations associated with obesity change with increase in body weight. This study employed data from the national Cerner HealthFacts Data Warehouse to identify changes in multimorbidity patterns by weight class using network analysis. Networks were generated for 154 528 middle-aged patients in the following categories: normal weight, overweight, and classes 1, 2, and 3 obesity. The results show significant differences (P-value<0.05) in prevalence by weight class for all but three of 82 diseases considered. The percentage of patients with multimorbidity (excluding obesity) increases from in 55.1% in patients with normal weight, to 57.88% with overweight, 70.39% with Class 1 obesity, 73.99% with Class 2 obesity, and 71.68% in Class 3 obesity, increasing most substantially with the progression from overweight to class 1 obesity. Most prevalent disease clusters expand from only hypertension and dorsalgia in normal weight, to add joint disorders in overweight, lipidemias in class 1 obesity, diabetes in class 2 obesity, and sleep disorders and chronic kidney disease in class 3 obesity. Recognition of multimorbidity patterns associated with weight increase is essential for true precision care of obesity-associated chronic conditions and can help clinicians identify and address preclinical disease before additional complications arise.
Details
- Title: Subtitle
- Increases in multimorbidity with weight class in the United States
- Creators
- Charisse R. Madlock-Brown - University of Tennessee Health Science CenterRebecca B. Reynolds - University of Tennessee Health Science CenterJames E. Bailey - University of Tennessee Health Science Center
- Resource Type
- Journal article
- Publication Details
- Clinical obesity, Vol.11(3), pp.e12436-n/a
- DOI
- 10.1111/cob.12436
- PMID
- 33372406
- PMCID
- 8454494
- NLM abbreviation
- Clin Obes
- ISSN
- 1758-8103
- eISSN
- 1758-8111
- Publisher
- Wiley
- Number of pages
- 17
- Grant note
- R15AG067232 / National Institute of Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) E070116014 / UTHSC Cornet Award
- Language
- English
- Date published
- 06/2021
- Academic Unit
- Nursing
- Record Identifier
- 9984446984502771
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