Sign in
Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan
Journal article   Open access   Peer reviewed

Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan

Shruti Bhide, Adriana S Trujillo, Maureen T O'Connor, Grant H Young, Diane E Cryderman, Sahaana Chandran, Mastaneh Nikravesh, Lori L Wallrath and Girish C Melkani
Aging Cell, Vol.17(3), e12747
03/25/2018
DOI: 10.1111/acel.12747Aging
PMCID: PMC5946079
PMID: 29575479
pdf
Increasing autophagy and blocking Nrf2 suppress laminopathy-induc3.83 MBDownloadView
Published (Version of record)CC BY V4.0 Open Access
url
https://doi.org/10.1111/acel.12747View
Published (Version of record)Aging Cell, 2018; 17: e12747.

Abstract

Biochemistry Medical Biochemistry autophagy cardiac aging Drosophila aging model lamins Nrf2/Keap1 pathway protein aggregation OAfund myocardial disease

Details

Metrics

87 File views/ downloads
45 Record Views