Journal article
Independent Validation of the Secondary Intracerebral Hemorrhage Score With Catheter Angiography and Findings of Emergent Hematoma Evacuation
Neurosurgery, Vol.70(1), pp.131-140
01/01/2012
DOI: 10.1227/NEU.0b013e31822fbf43
PMID: 21808219
Abstract
Abstract
BACKGROUND
The secondary intracerebral hemorrhage (SICH) score, derived from a cohort of patients with intracerebral hemorrhage examined with computed tomographic (CT) angiography, predicts a patient's risk of harboring a vascular etiology.
OBJECTIVE
To validate the SICH score in an independent patient population.
METHODS
We retrospectively reviewed all adults with nontraumatic ICH who presented to our institution during a 5.4-year period and were evaluated with catheter angiography or underwent emergent hematoma evacuation, and applied the SICH score to this cohort. Receiver operating characteristic analysis was performed to determine the area under the curve (AUC) and maximum operating point (MOP). Patients with subarachnoid hemorrhage in the basal cisterns were excluded.
RESULTS
The study included 341 patients, with a mean age of 57.2 years (range, 18–88). Of these, 179 patients were male (52.5%) and 162 were female (47.5%). Two hundred ninety-two patients were evaluated with catheter angiography (85.6%), and 49 underwent emergent hematoma evacuation (14.4%). The SICH score successfully predicted an increasing risk of underlying vascular etiologies in the independent patient cohort, which was similar to the cohort examined with CT angiography. The MOP was reached at a SICH score >2, with the highest incidence of vascular etiologies in patients with SICH scores of 3 (18.8%), 4 (39%), and 5 (79.2%). There was no significant difference in the AUC between the 2 cohorts (0.82-0.87).
CONCLUSION
The SICH score successfully predicted the risk of a patient with ICH of harboring a vascular etiology in an independent patient population. This scoring system could be used to select patients with ICH for neurovascular evaluation to exclude an underlying vascular abnormality.
Details
- Title: Subtitle
- Independent Validation of the Secondary Intracerebral Hemorrhage Score With Catheter Angiography and Findings of Emergent Hematoma Evacuation
- Creators
- Josser E Delgado Almandoz - Division of Neuroradiology, Mallinckrodt Institute of Radiology, Washington University, Saint Louis, MissouriBharathi D Jagadeesan - Division of Neuroradiology, Mallinckrodt Institute of Radiology, Washington University, Saint Louis, MissouriChristopher J Moran - Division of Neuroradiology, Mallinckrodt Institute of Radiology, Washington University, Saint Louis, MissouriDeWitte T Cross - Division of Neuroradiology, Mallinckrodt Institute of Radiology, Washington University, Saint Louis, MissouriGregory J Zipfel - §Department of Neurological SurgeryJin-Moo Lee - ¶Department of Neurology, Washington University, Saint Louis, MissouriJavier M Romero - ‡Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MassachusettsColin P Derdeyn - Division of Neuroradiology, Mallinckrodt Institute of Radiology, Washington University, Saint Louis, Missouri
- Resource Type
- Journal article
- Publication Details
- Neurosurgery, Vol.70(1), pp.131-140
- Publisher
- Oxford University Press
- DOI
- 10.1227/NEU.0b013e31822fbf43
- PMID
- 21808219
- ISSN
- 0148-396X
- eISSN
- 1524-4040
- Language
- English
- Date published
- 01/01/2012
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020747402771
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