Journal article
Independent external validation of a nomogram to define risk categories for a significant decline in estimated glomerular filtration rate after robotic-assisted partial nephrectomy
International journal of urology, Vol.28(1), pp.75-79
01/01/2021
DOI: 10.1111/iju.14404
PMID: 33135845
Abstract
Objective To validate the Martini nomogram predicting the decline in estimated glomerular filtration rate after robotic-assisted partial nephrectomy.
Methods Estimated glomerular filtration rate of 406 patients from a single surgeon series was calculated before robotic-assisted partial nephrectomy and at postoperative intervals. To determine the risk group, we calculated the total score and corresponding risk of significant estimated glomerular filtration rate reduction at 15 months using the Martini nomogram. The primary outcome was a reduction in estimated glomerular filtration rate of >= 25% from preoperative levels between 1 and 12 months after surgery.
Results The median length of follow up for this study was 12 months (interquartile range 6-12 months). Overall, 134 (33%) patients were in the low-, 143 (35%) in the intermediate-, 119 (29%) in the high- and 10 (2%) in the very high-risk groups. The Kaplan-Meier estimates for the probability of significant estimated glomerular filtration rate reduction by 12 months after robotic-assisted partial nephrectomy was 12.9% in the low-risk group, 24.0% in the intermediate-risk group, 49.7% in the high-risk group and 40.0% in the very high-risk group. Harrell's C-index for discriminating between those with and without a significant reduction in estimated glomerular filtration rate 1-12 months after robotic-assisted partial nephrectomy was 0.73 (95% confidence interval 0.68-0.78).
Conclusions The risk groups proposed by the Martini nomogram are accurate in predicting those at higher risk for a >25% decline in postoperative estimated glomerular filtration rate after robotic-assisted partial nephrectomy at 12 months.
Details
- Title: Subtitle
- Independent external validation of a nomogram to define risk categories for a significant decline in estimated glomerular filtration rate after robotic-assisted partial nephrectomy
- Creators
- Essa M. Bajalia - Mayo Clinic in FloridaAmanda A. Myers - Mayo Clinic in FloridaDaniela A. Haehn - Mayo Clinic in FloridaAmanda E. Kahn - Mayo Clinic in FloridaColleen T. Ball - Mayo Clinic in FloridaDavid D. Thiel - Mayo Clinic in Florida
- Resource Type
- Journal article
- Publication Details
- International journal of urology, Vol.28(1), pp.75-79
- DOI
- 10.1111/iju.14404
- PMID
- 33135845
- NLM abbreviation
- Int J Urol
- ISSN
- 0919-8172
- eISSN
- 1442-2042
- Publisher
- Wiley
- Number of pages
- 5
- Language
- English
- Date published
- 01/01/2021
- Academic Unit
- Urology
- Record Identifier
- 9984934816902771
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