Journal article
Individuals with migraine have a different dry eye symptom profile than individuals without migraine
British journal of ophthalmology, Vol.104(2), pp.260-264
02/2020
DOI: 10.1136/bjophthalmol-2018-313471
PMID: 31040130
Abstract
BackgroundMany individuals with migraine report symptoms of dry eye (DE). However, it is not known whether DE profiles are similar between individuals with and without migraine. To bridge this gap, we evaluated symptoms and signs of DE, including symptoms suggestive of nerve dysfunction, in a large group of individuals with DE symptoms, and compared profiles between individuals with migraine and those without migraine or headache.MethodsProspective cross-sectional study of individuals with DE symptoms seen at the Miami VA.ResultsOf 250 individuals, 31 met International Classification of Headache Disorders criteria for migraine based on a validated screen. Individuals with migraine were significantly younger (57 vs 62 years) and more likely to be female (26% vs 6%) than controls. Individuals with migraine had more severe DE symptoms and ocular pain compared with controls (mean Ocular Surface Disease Index 53.93 ± 21.76 vs 36.30 ± 22.90, p=0.0001; mean Neuropathic Pain Symptom Inventory modified for the Eye 39.39 ± 23.33 vs 21.86 ± 20.17, p=0.0001). The difference in symptom profile occurred despite similar ocular surface parameters between the groups.ConclusionsIndividuals with migraine had a different DE symptom yet a similar DE sign profile when compared with controls without migraine. This suggests that DE symptoms in individuals with migraine may be driven by nerve dysfunction as opposed to ocular surface abnormalities.
Details
- Title: Subtitle
- Individuals with migraine have a different dry eye symptom profile than individuals without migraine
- Creators
- Monika Farhangi - University of MiamiRyan J Diel - University of Iowa Hospitals and ClinicsDawn C Buse - Albert Einstein College of MedicineAmy Michelle Huang - University of MiamiRoy C Levitt - University of MiamiConstantine D Sarantopoulos - University of MiamiElizabeth R Felix - United States Department of Veterans AffairsAnat Galor - University of Miami
- Resource Type
- Journal article
- Publication Details
- British journal of ophthalmology, Vol.104(2), pp.260-264
- DOI
- 10.1136/bjophthalmol-2018-313471
- PMID
- 31040130
- ISSN
- 0007-1161
- eISSN
- 1468-2079
- Language
- English
- Date published
- 02/2020
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984697640602771
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