Journal article
Inflammation in Coronary Artery Disease
Cardiology in review, Vol.22(6), pp.279-288
11/2014
DOI: 10.1097/CRD.0000000000000006
PMID: 24441047
Abstract
Coronary artery disease (CAD) is the leading cause of death in the United States. Although CAD was formerly considered a lipid accumulation–mediated disease, it has now been clearly shown to involve an ongoing inflammatory response. Advances in basic science research have established the crucial role of inflammation in mediating all stages of CAD. Today, there is convincing evidence that multiple interrelated immune mechanisms interact with metabolic risk factors to initiate, promote, and ultimately activate lesions in the coronary arteries. This review aims to provide current evidence pertaining to the role of inflammation in the pathogenesis of CAD and discusses the impact of inflammatory markers and their modification on clinical outcomes.
Details
- Title: Subtitle
- Inflammation in Coronary Artery Disease
- Creators
- Georgios Christodoulidis - From the Department of Internal Medicine, Winthrop University Hospital, Mineola, NY; †St. Francis Hospital, The Heart Center, Division of Cardiology, Center of Advanced Cardiac Therapeutics, Roslyn, NY; ‡Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, TN; §Department of Medicine, Emory University School of Medicine, Atlanta, GA; and ¶Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NYTimothy VittorioMarat FudimStamatios LerakisConstantine Kosmas
- Resource Type
- Journal article
- Publication Details
- Cardiology in review, Vol.22(6), pp.279-288
- Publisher
- by Lippincott Williams & Wilkins
- DOI
- 10.1097/CRD.0000000000000006
- PMID
- 24441047
- ISSN
- 1061-5377
- eISSN
- 1538-4683
- Language
- English
- Date published
- 11/2014
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094545202771
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