Journal article
Influence of age on the cortisol response to dexamethasone
Psychiatry research, Vol.13(3), pp.213-220
1984
DOI: 10.1016/0165-1781(84)90036-2
PMID: 6597460
Abstract
Controversy exists regarding the association of age with postdexamethasone serum cortisol levels. We evaluated this relationship in 95 patients with major depressive disorder and 49 healthy controls. Age and 8 a.m. postdexamethasone cortisol levels were not correlated among the healthy controls, but were positively associated among the depressives. There was also a trend for age and 4 p.m. postdexamethasone cortisol levels to be positively associated in depressives. Multiple linear regression analyses revealed that these associations could not be explained by other variables such as sex, psychotic features, or familial subtype of depression. Several hypotheses that might account for these associations are examined.
Details
- Title: Subtitle
- Influence of age on the cortisol response to dexamethasone
- Creators
- David A Lewis - David A. Lewis, M.D., Department of Psychiatry, University of Iowa Hospitals, Iowa City, IA, USABruce Pfohl - Bruce Pfohl, M.D., Department of Psychiatry, University of Iowa Hospitals, Iowa City, IA, USAJanet Schlechte - Janet Schlechte, Department of Internal Medicine, University of Iowa Hospitals, Iowa City, IA, USAWilliam Coryell - William Coryell, M.D., Department of Psychiatry, University of Iowa Hospitals, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Psychiatry research, Vol.13(3), pp.213-220
- Publisher
- Elsevier Ireland Ltd
- DOI
- 10.1016/0165-1781(84)90036-2
- PMID
- 6597460
- ISSN
- 0165-1781
- eISSN
- 1872-7123
- Language
- English
- Date published
- 1984
- Academic Unit
- Psychiatry; Internal Medicine
- Record Identifier
- 9984003413102771
Metrics
24 Record Views