Journal article
Influence of amalgam fillings on Hg levels and total antioxidant activity in plasma of healthy donors
The Science of the total environment, Vol.301(1-3), pp.43-50
2003
DOI: 10.1016/S0048-9697(02)00291-7
PMID: 12493183
Abstract
In order to evaluate the influence of specific factors on mercury (P-Hg) levels and antioxidant power (P-FRAP) in human plasma, 26 healthy donors were examined by a dentist, their plasma analyzed for Hg by atomic absorption spectrometry and for total antioxidant activity by FRAP method. Hg plasma concentration was found to be correlated with the number of amalgam fillings, suggesting that Hg released from fillings is a source of Hg in non-occupational exposed subjects. P-FRAP correlated negatively with P-Hg suggesting a pro-oxidant role of the Hg released from amalgam fillings. Though age by itself was not significantly correlated with P-FRAP, when considered together with P-Hg in multivariate analysis, it was found to be a major related cofactor. Multivariate analysis showed no influence of fish consumption or cigarette smoking on P-FRAP.
Details
- Title: Subtitle
- Influence of amalgam fillings on Hg levels and total antioxidant activity in plasma of healthy donors
- Creators
- Maria Pizzichini - University of SienaMichele Fonzi - University of SienaFabiola Giannerini - University of SienaMarzia Mencarelli - University of SienaAlberto Gasparoni - University of SienaGiovannino Rocchi - University of SienaVasilios Kaitsas - University of SienaLuciano Fonzi - University of Siena
- Resource Type
- Journal article
- Publication Details
- The Science of the total environment, Vol.301(1-3), pp.43-50
- Publisher
- Elsevier Science
- DOI
- 10.1016/S0048-9697(02)00291-7
- PMID
- 12493183
- ISSN
- 0048-9697
- eISSN
- 1879-1026
- Language
- English
- Date published
- 2003
- Academic Unit
- Oral Pathology, Radiology and Medicine; Dental Clinic Administration
- Record Identifier
- 9984367616602771
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