Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults

Darren P Casey; Aaron C Schneider; Kenichi Ueda

doi:10.1007/s00421-016-3445-4

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Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults

Journal article

Open access

Peer reviewed

Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults

Darren P Casey, Aaron C Schneider and Kenichi Ueda

European journal of applied physiology, Vol.116(10), pp.1931-1940

10/2016

DOI: 10.1007/s00421-016-3445-4

PMCID: PMC5572819

PMID: 27497720

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http://doi.org/10.1007/s00421-016-3445-4View

Open Access

Abstract

With aging, there tends to be an increase in retrograde and oscillatory shear in peripheral conduit arteries of humans. Whether the increase in shear rate is due to the aging process or an effect of a less active lifestyle that often accompanies aging is unknown. Therefore, we examined whether chronic endurance exercise training attenuates conduit artery retrograde and oscillatory shear in older adults. Brachial and common femoral artery mean blood velocities and diameter were determined via Doppler ultrasound under resting conditions, and shear rate was calculated in 13 young (24 ± 2 years), 17 older untrained (66 ± 3 years), and 16 older endurance exercise-trained adults (66 ± 7 years). Brachial artery retrograde (-9.1 ± 6.4 vs. -12.6 ± 9.4 s(-1); P = 0.35) and oscillatory (0.14 ± 0.08 vs. 0.14 ± 0.08 arbitrary units; P = 0.99) shear were similar between the older trained and untrained groups, whereas brachial artery retrograde and oscillatory shear were greater in older untrained compared to young adults (-5.0 ± 3.4, 0.08 ± 0.05 s(-1) arbitrary units, P = 0.017 and 0.048, respectively). There was no difference between the young and older trained brachial retrograde (P = 0.29) and oscillatory (P = 0.07) shear. Common femoral artery retrograde (-6.3 ± 2.9 s(-1)) and oscillatory (0.21 ± 0.08 arbitrary units) shear were reduced in older trained compared to the older untrained group (-10.4 ± 4.1 and 0.30 ± 0.09 s(-1) arbitrary units, both P = 0.005 and 0.006, respectively), yet similar to young adults (-7.1 ± 3.5 and 0.19 ± 0.06 s(-1) arbitrary units, P = 0.81 and 0.87, respectively). Our results suggest that chronic endurance exercise training in older adults ameliorates retrograde and oscillatory shear rate patterns, particularly in the common femoral artery.

Humans

Image Interpretation, Computer-Assisted - methods

Physical Conditioning, Human - physiology

Male

Shear Strength - physiology

Physical Endurance - physiology

Brachial Artery - diagnostic imaging

Blood Viscosity - physiology

Femoral Artery - diagnostic imaging

Ultrasonography, Doppler - methods

Biological Clocks - physiology

Blood Flow Velocity

Adult

Female

Aged

Exercise - physiology

Femoral Artery - physiology

Physical Conditioning, Human - methods

Brachial Artery - physiology

Details

Title: Subtitle: Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults
Creators: Darren P Casey - Fraternal Order of Eagles Diabetes Research, Carver College of Medicine, University of Iowa, Iowa, IA, 52242, USA. darren-casey@uiowa.edu
Aaron C Schneider - Department of Health and Human Physiology, University of Iowa, Iowa, IA, 52242, USA
Kenichi Ueda - Department of Anesthesia, Carver College of Medicine, University of Iowa, Iowa, IA, 52242, USA
Resource Type: Journal article
Publication Details: European journal of applied physiology, Vol.116(10), pp.1931-1940
DOI: 10.1007/s00421-016-3445-4
PMID: 27497720
PMCID: PMC5572819
NLM abbreviation: Eur J Appl Physiol
ISSN: 1439-6319
eISSN: 1439-6327
Publisher: Germany
Grant note: K99 HL105467 / NHLBI NIH HHS R00 HL105467 / NHLBI NIH HHS
Language: English
Date published: 10/2016
Academic Unit: Anesthesia; Physical Therapy and Rehabilitation Science; Fraternal Order of Eagles Diabetes Research Center; Health, Sport, and Human Physiology
Record Identifier: 9984047707002771

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