Journal article
Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study
Frontiers in human neuroscience, Vol.19, 1557661
02/28/2025
DOI: 10.3389/fnhum.2025.1557661
PMCID: PMC11906719
PMID: 40092652
Abstract
Introduction: Lower sensitivity (LS) to acute alcohol promotes hazardous alcohol use, increasing risk for alcohol use disorder (AUD). Compared to peers with high sensitivity (HS), LS individuals exhibit amplified responses to alcohol cues and difficulty exerting inhibitory control (IC) over those cued responses. However, it is unclear whether LS and HS individuals differ in neural or behavioral responses when exerting IC over affectively neutral prepotent responses (i.e., domain-general IC). This fMRI pilot study examined domain-general IC and its neural correlates in young adult LS and HS individuals.
Details
- Title: Subtitle
- Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study
- Creators
- Roberto Cofresí - University of MissouriSpencer Upton - University of MissouriDevon Terry - University of MissouriAlexander Brown - University of MissouriThomas Piasecki - University of Wisconsin–MadisonBruce Bartholow - University of IowaBrett Froeliger - University of Missouri
- Resource Type
- Journal article
- Publication Details
- Frontiers in human neuroscience, Vol.19, 1557661
- DOI
- 10.3389/fnhum.2025.1557661
- PMID
- 40092652
- PMCID
- PMC11906719
- NLM abbreviation
- Front Hum Neurosci
- ISSN
- 1662-5161
- eISSN
- 1662-5161
- Publisher
- Frontiers Research Foundation; LAUSANNE
- Grant note
- University of Missouri Cognitive Neuroscience Systems Core Facility Board of DirectorsNIH: AA025451, AA013526, AA025451-[04/05]S1, AA029169
The authors declare that financial support was received for the research, authorship, and/or publication of this article. Funding for the project was provided by an internal seed grant from the University of Missouri Cognitive Neuroscience Systems Core Facility Board of Directors. BB and TP's contributions were supported by the NIH grant that funded the parent study (AA025451). SU's contributions were supported by an NIH T32 traineeship (AA013526). RC's contributions were supported by NIH Diversity Supplement (AA025451-[04/05]S1) and by NIH K99/R00 (AA029169).
- Language
- English
- Date published
- 02/28/2025
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984795478002771
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