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Initial clinical experience with frameless stereotactic radiosurgery: Analysis of accuracy and feasibility
Journal article   Peer reviewed

Initial clinical experience with frameless stereotactic radiosurgery: Analysis of accuracy and feasibility

Timothy C RYKEN, Sanford L MEEKS, Edward C PENNINGTON, Patrick HITCHON, Vincent TRAYNELIS, Nina A MAYR, Frank J BOVA, William A FRIEDMAN and John M BUATTI
International journal of radiation oncology, biology, physics, Vol.51(4), pp.1152-1158
2001
DOI: 10.1016/S0360-3016(01)01756-4
PMID: 11704340

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Abstract

Math Eq: To report on preliminary clinical experience with a novel image-guided frameless stereotactic radiosurgery system. Math Eq: Fifteen patients ranging in age from 14 to 81 received radiosurgery using a commercially available frameless stereotactic radiosurgery system. Pathologic diagnoses included metastases (12), recurrent primary intracranial sarcoma (1), recurrent central nervous system (CNS) lymphoma (1), and medulloblastoma with supratentorial seeding (1). Treatment accuracy was assessed from image localization of the stereotactic reference array and reproducibility of biteplate reseating. We chose 0.3 mm vector translation error and 0.3 degree rotation about each axis as the maximum tolerated misalignment before treating each arc. Math Eq: The biteplates were found on average to reseat with a reproducibility of 0.24 mm. The mean registration error from CT localization was found to be 0.5 mm, which predicts that the average error at isocenter was 0.82 mm. No patient treatment was delivered beyond the maximum tolerated misalignment. The radiosurgery treatment was delivered in approximately 25 min per patient. Math Eq: Our initial clinical experience with stereotactic radiotherapy using the infrared camera guidance system was promising, demonstrating clinical feasibility and accuracy comparable to many frame-based systems.
Biological and medical sciences Medical sciences Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Diseases of the nervous system

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