Journal article
Injected periurethral collagen for postprostatectomy urinary incontinence : MR and CT appearance
Abdominal imaging, Vol.25(6), pp.658-662
2000
DOI: 10.1007/s002610000073
PMID: 11029103
Abstract
Background: Urinary incontinence, a disturbing complication of radical prostatectomy, is often treated with periurethral collagen injections to increase urethral closure and resistance to urinary outflow.
Methods: Using magnetic resonance imaging and computed tomography, we studied the appearance of glutaraldehyde cross-lined bovine collagen endoscopically injected into the periurethral tissues in four men who developed urinary incontinence after radical prostatectomy. Collagen was also scanned in vitro to verify its magnetic resonance appearance.
Results: Collagen deposits appear as well-circumscribed nodules of low to intermediate signal intensity on both T1- and T2-weighted images in the periurethral tissues or in the base of the subjacent penile bulb (base of corpus spongiosum). On contrast-enhanced computed tomography, collagen appears as a hypoattenuating nodular-filling defect within the penile bulb.
Conclusion: These imaging characteristics should allow differentiation of collagen from locally recurrent prostate carcinoma and avoid inappropriate work-up of benign findings. RID="" ID="" Correspondence to: M. P. Banner
Details
- Title: Subtitle
- Injected periurethral collagen for postprostatectomy urinary incontinence : MR and CT appearance
- Creators
- D. D MAKI - Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, United StatesM. P BANNER - Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, United StatesP RAMCHANDANI - Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, United StatesA STOLPEN - Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, United StatesE. S ROVNER - Department of Surgery, Division of Urology. University of Pennsylvania Medical Center, 3400 Spruce Street., Philadelphia, PA 19104, United StatesA. J WEIN - Department of Surgery, Division of Urology. University of Pennsylvania Medical Center, 3400 Spruce Street., Philadelphia, PA 19104, United States
- Resource Type
- Journal article
- Publication Details
- Abdominal imaging, Vol.25(6), pp.658-662
- Publisher
- Springer; New York, NY
- DOI
- 10.1007/s002610000073
- PMID
- 11029103
- ISSN
- 0942-8925
- eISSN
- 1432-0509
- Language
- English
- Date published
- 2000
- Academic Unit
- Radiology; Internal Medicine
- Record Identifier
- 9984052000102771
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