Journal article
Innate immune control and regulation of influenza virus infections
Journal of leukocyte biology, Vol.86(4), pp.803-812
10/2009
DOI: 10.1189/jlb.0509368
PMCID: PMC2752015
PMID: 19643736
Abstract
Adaptive immune responses are critical for the control and clearance of influenza A virus (IAV) infection. However, in recent years, it has become increasingly apparent that innate immune cells, including natural killer cells, alveolar macrophages (aMphi), and dendritic cells (DC) are essential following IAV infection in the direct control of viral replication or in the induction and regulation of virus-specific adaptive immune responses. This review will discuss the role of these innate immune cells following IAV infection, with a particular focus on DC and their ability to induce and regulate the adaptive IAV-specific immune response.
Details
- Title: Subtitle
- Innate immune control and regulation of influenza virus infections
- Creators
- Jodi McGill - Department of Pathology and Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa 52242, USAJonathan W HeuselKevin L Legge
- Resource Type
- Journal article
- Publication Details
- Journal of leukocyte biology, Vol.86(4), pp.803-812
- DOI
- 10.1189/jlb.0509368
- PMID
- 19643736
- PMCID
- PMC2752015
- NLM abbreviation
- J Leukoc Biol
- ISSN
- 0741-5400
- eISSN
- 1938-3673
- Publisher
- United States
- Grant note
- R01 AI071085 / NIAID NIH HHS AI071085 / NIAID NIH HHS AI076989 / NIAID NIH HHS R56 AI071085 / NIAID NIH HHS R21 AI076989 / NIAID NIH HHS
- Language
- English
- Date published
- 10/2009
- Academic Unit
- Microbiology and Immunology; Pathology
- Record Identifier
- 9984047748802771
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