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Instructing the Instructor: Tissue-Resident T Cells Activate Innate Immunity
Journal article   Open access   Peer reviewed

Instructing the Instructor: Tissue-Resident T Cells Activate Innate Immunity

Bram Slütter and John T Harty
Cell host & microbe, Vol.16(4), pp.421-423
10/08/2014
DOI: 10.1016/j.chom.2014.09.011
PMID: 25299324
url
https://doi.org/10.1016/j.chom.2014.09.011View
Published (Version of record) Open Access

Abstract

A small number of tissue-resident memory T cells (Trm) provide potent protection against infections. Three recent studies by Ariotti et al. (2014), Schenkel et al. (2014a), and Iijima and Iwasaki (2014) report that Trm rapidly produce cytokines after infection and initiate a tissue-wide anti-viral state by instructing innate immune cells.

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