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Interleaved Variable Density Sampling With a Constrained Parallel Imaging Reconstruction for Dynamic Contrast-Enhanced MR Angiography
Journal article   Peer reviewed

Interleaved Variable Density Sampling With a Constrained Parallel Imaging Reconstruction for Dynamic Contrast-Enhanced MR Angiography

Kang Wang, Reed F. Busse, James H. Holmes, Philip J. Beatty, Jean H. Brittain, Christopher J. Francois, Scott B. Reeder, Jiang Du and Frank R. Korosec
Magnetic resonance in medicine, Vol.66(2), pp.428-436
08/01/2011
DOI: 10.1002/mrm.22814
PMCID: PMC3552437
PMID: 21360740

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Abstract

For MR applications such as contrast-enhanced MR angiography, it is desirable to achieve simultaneously high spatial and temporal resolution. The current clinical standard uses view-sharing methods combined with parallel imaging; however, this approach still provides limited spatial and temporal resolution. To improve on the clinical standard, we present an interleaved variable density (IVD) sampling method that pseudorandomly undersamples each individual frame of a 3D Cartesian k(y)-k(z) plane combined with parallel imaging acceleration. From this dataset, time-resolved images are reconstructed with a method that combines parallel imaging with a multiplicative constraint. Total acceleration factors on the order of 20 are achieved for contrast-enhanced MR angiography of the lower extremities, and improvements in temporal fidelity of the depiction of the contrast bolus passage are demonstrated relative to the clinical standard. Magn Reson Med 66:428-436, 2011. (C) 2011 Wiley-Liss, Inc.
Life Sciences & Biomedicine Radiology, Nuclear Medicine & Medical Imaging Science & Technology

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