Journal article
Internalized myofiber capillaries: Observations on their origin and clinical features
Muscle & nerve, Vol.12(3), pp.191-196
03/1989
DOI: 10.1002/mus.880120305
PMID: 2725549
Abstract
Internalized capillaries limited to type 1 muscle fibers were noted in seven patients. They occurred in each case in association with a similar admixture of neurogenic and myopathic features that included atrophic and hypertrophic fibers, internal nuclei, fiber splitting, and endomyseal and perimyseal fibrosis. Internalized capillaries in enlarged type 1 fibers arose from fiber splits on step section study of four patients. They occurred in the gastrocnemius, quadriceps, and soleus muscles from patients with a variety of disorders that included Becker dystrophy, diabetes mellitus and strenuous leg activities, Achilles tendon rupture, and myotonic dystrophy. Exercise‐induced myalgias were noted in the four patients with most plentiful intramuscular capillaries, and in three of these muscle hypertrophy was present. The concurrence of internalized myofiber capillaries and exercise induced myalgias may represent an associated biochemical/pathological defect.
Details
- Title: Subtitle
- Internalized myofiber capillaries: Observations on their origin and clinical features
- Creators
- Ludwig GutmannRobert WolfWilfred NixHans H GoebelSydney S SchochetHanns C HopfGünter Kramer
- Resource Type
- Journal article
- Publication Details
- Muscle & nerve, Vol.12(3), pp.191-196
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- DOI
- 10.1002/mus.880120305
- PMID
- 2725549
- ISSN
- 0148-639X
- eISSN
- 1097-4598
- Number of pages
- 6
- Language
- English
- Date published
- 03/1989
- Academic Unit
- Neurology
- Record Identifier
- 9984020505402771
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