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Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults
Journal article   Open access   Peer reviewed

Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults

Soolim Jeong, Braxton A Linder, Alex M Barnett, McKenna A Tharpe, Zach J Hutchison, Meral N Culver, Sofia O Sanchez, Olivia I Nichols, Gregory J Grosicki, Kanokwan Bunsawat, …
American journal of physiology. Heart and circulatory physiology, Vol.327(3), pp.H601-H613
09/01/2024
DOI: 10.1152/ajpheart.00726.2023
PMCID: PMC11442101
PMID: 38995211
url
https://doi.org/10.1152/ajpheart.00726.2023View
Published (Version of record) Open Access

Abstract

Nighttime blood pressure (BP) and BP dipping (daytime-nighttime BP) are prognostic for cardiovascular disease. When compared with other racial/ethnic groups, Black Americans exhibit elevated nighttime BP and attenuated BP dipping. Neighborhood deprivation may contribute to disparities in cardiovascular health, but its effects on resting and ambulatory BP patterns in young adults are unclear. Therefore, we examined associations between neighborhood deprivation with resting and nighttime BP and BP dipping in young Black and White adults. We recruited 19 Black and 28 White participants (23 males/24 females, 21 ± 1 yr, body mass index: 26 ± 4 kg/m ) for 24-h ambulatory BP monitoring. We assessed resting BP, nighttime BP, and BP dipping (absolute dip and nighttime:daytime BP ratio). We used the area deprivation index (ADI) to assess average neighborhood deprivation during early and mid-childhood and adolescence. When compared with White participants, Black participants exhibited higher resting systolic and diastolic BP ( ≤ 0.029), nighttime systolic BP (114 ± 9 vs. 108 ± 9 mmHg, = 0.049), diastolic BP (63 ± 8 vs. 57 ± 7 mmHg, = 0.010), and attenuated absolute systolic BP dipping (12 ± 5 vs. 9 ± 7 mmHg, = 0.050). Black participants experienced greater average ADI scores compared with White participants [110 (10) vs. 97 (22), = 0.002], and select ADI scores correlated with resting BP and some ambulatory BP measures. Within each race, select ADI scores correlated with some BP measures for Black participants, but there were no ADI and BP correlations for White participants. In conclusion, our findings suggest that neighborhood deprivation may contribute to higher resting BP and impaired ambulatory BP patterns in young adults warranting further investigation in larger cohorts. We demonstrate that young Black adults exhibit higher resting blood pressure, nighttime blood pressure, and attenuated systolic blood pressure dipping compared with young White adults. Black adults were exposed to greater neighborhood deprivation, which demonstrated some associations with resting and ambulatory blood pressure. Our findings add to a growing body of literature indicating that neighborhood deprivation may contribute to increased blood pressure.
 Adolescent Black or African American Blood Pressure Blood Pressure Monitoring, Ambulatory Circadian Rhythm Female Health Status Disparities Humans Hypertension - diagnosis Hypertension - ethnology Male Race Factors Residence Characteristics White Young Adult

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