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Interventionalist perspective on the new endovascular trials
Journal article   Peer reviewed

Interventionalist perspective on the new endovascular trials

Laurent Pierot and Colin Derdeyn
Stroke (1970), Vol.46(6), pp.1440-1446
06/2015
DOI: 10.1161/STROKEAHA.115.008416
PMID: 25944327

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Abstract

Three recently published trials have conclusively proven the benefit of mechanical endovascular thrombectomy over best medical therapy for patients with acute ischemic stroke and large vessel occlusion. These trials shared some features and differed in others. These similarities and differences in trial design and execution affect the conclusions and recommendations that can be made from the data. We will examine the implications of these studies for neurointerventionists, both for current practice and for future studies. In particular, we will focus on procedural details such as patient selection, devices, adjunctive therapies, treatment time windows, and performance metrics.
Endovascular Procedures - instrumentation Stroke - surgery Endovascular Procedures - methods Humans Thrombectomy - methods Thrombectomy - instrumentation Clinical Trials as Topic - methods Clinical Trials as Topic - standards Brain Ischemia - surgery

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