Journal article
Intestinal metaplasia and gastric atrophy in children is not as frequent as adults
Türkiye klinikleri. Türkiye klinikeri journal of medical sciences. Tıp bilimleri dergisi, Vol.33(4), pp.1053-1057
2013
DOI: 10.5336/medsci.2012-32134
Abstract
Objective: Atrophic gastritis and intestinal metaplasia are frequently seen among adult patients and are thought to be premalignant. The prevalence of these lesions among children is not well known. The aim of the study is to investigate the prevalence of gastric atrophy and intestinal metaplasia in children. Material and and Methods: Children with gastrointestinal symptoms admitted to our clinic were evaluated. The data about urea breath test, upper gastrointestinal endoscopy macroscopical findings and histopathological evaluation with modified Sydney classification were evaluated retrospectively from patient records. Results: A total of 357 children underwent upper gastrointestinal system endoscopy. Histopathological evaluation revealed no gastric atrophy but intestinal metaplasia in 2 children. Both of the children had positive urea breath test, gastritis and were positive for Helicobacter pylori histologically. One of these children also had a peptic ulcer. The children underwent endoscopy again after H.pylori eradication therapy, and intestinal metaplasia was not seen on the biopsy materials. Conclusion: Precancerous lesions are very rarely reported among children. These are particularly seen together with H. pylori infection and around 10-years of age. Our results show that intestinal metaplasia is seen in H.pylori positive children and the incidence is very low. The reason of low prevalence is suggested to be depending on the host, microorganism and the pathologists.
Details
- Title: Subtitle
- Intestinal metaplasia and gastric atrophy in children is not as frequent as adults
- Creators
- Meltem Uǧraş - Yeditepe UniversitySaadet Alan - State Hospital
- Resource Type
- Journal article
- Publication Details
- Türkiye klinikleri. Türkiye klinikeri journal of medical sciences. Tıp bilimleri dergisi, Vol.33(4), pp.1053-1057
- DOI
- 10.5336/medsci.2012-32134
- ISSN
- 1300-0292
- eISSN
- 2146-9040
- Number of pages
- 5
- Translated title
- İntestinal Metaplazi ve Gastrik Atrofi Çocuklarda Erişkinlerdeki Kadar Sık Değildir
- Language
- English
- Date published
- 2013
- Academic Unit
- Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9985214101002771
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