Intra-aneurysmal thrombus modification after flow-diversion

Mario Zanaty; Pascal M. Jabbour; Roula Bou Sader; Nohra Chalouhi; Stavropoula Tjoumakaris; Robert H. Rosenwasser; L. Fernando Gonzalez

doi:10.1016/j.jocn.2014.05.033

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Intra-aneurysmal thrombus modification after flow-diversion

Journal article

Peer reviewed

Intra-aneurysmal thrombus modification after flow-diversion

Mario Zanaty, Pascal M. Jabbour, Roula Bou Sader, Nohra Chalouhi, Stavropoula Tjoumakaris, Robert H. Rosenwasser and L. Fernando Gonzalez

Journal of clinical neuroscience, Vol.22(1), pp.105-110

01/01/2015

DOI: 10.1016/j.jocn.2014.05.033

PMID: 25192591

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Abstract

Flow diversion has been successfully used to treat large and giant intracranial aneurysms that present with mass effect. We conducted a retrospective review, evaluating the modification of thrombi in this aneurysm type after treatment with the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) and the effects of these modifications on symptoms. Eight patients, seven of whom were female, harbored eight partially thrombosed large or giant aneurysms. Five of the eight aneurysms presented with symptomatic mass effect. At 1 year follow-up, complete occlusion occurred in 75% (6/8) of patients. On average, the longest thrombus diameter measured 22.31 mm before treatment and 14.05 mm 1 year afterwards. Seven of the eight thrombi regressed, as did their aneurysms. All six patients with shrunken thrombi had tremendous symptom improvement and became asymptomatic in the following year. The current findings seem to reflect the size variation of the intra-aneurysmal thrombus rather than the size of the aneurysm itself. (C) 2014 Elsevier Ltd. All rights reserved.

Clinical Neurology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Details

Title: Subtitle: Intra-aneurysmal thrombus modification after flow-diversion
Creators: Mario Zanaty - Jefferson Hospital for Neuroscience
Pascal M. Jabbour - Jefferson Hospital for Neuroscience
Roula Bou Sader - Jefferson Hospital for Neuroscience
Nohra Chalouhi - Jefferson Hospital for Neuroscience
Stavropoula Tjoumakaris - Jefferson Hospital for Neuroscience
Robert H. Rosenwasser - Jefferson Hospital for Neuroscience
L. Fernando Gonzalez - Jefferson Hospital for Neuroscience
Resource Type: Journal article
Publication Details: Journal of clinical neuroscience, Vol.22(1), pp.105-110
DOI: 10.1016/j.jocn.2014.05.033
PMID: 25192591
NLM abbreviation: J Clin Neurosci
ISSN: 0967-5868
eISSN: 1532-2653
Publisher: Elsevier
Number of pages: 6
Language: English
Date published: 01/01/2015
Academic Unit: Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984527198302771

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