Journal article
Intraarterial encephalography from an acutely implanted aneurysm embolization device in awake humans
Journal of neurosurgery, Vol.138(3), pp.785-792
03/2023
DOI: 10.3171/2022.6.JNS22932
Abstract
OBJECTIVE
Endovascular electroencephalography (evEEG) uses the cerebrovascular system to record electrical activity from adjacent neural structures. The safety, feasibility, and efficacy of using the Woven EndoBridge Aneurysm Embolization System (WEB) for evEEG has not been investigated.
METHODS
Seventeen participants undergoing awake WEB endovascular treatment of unruptured cerebral aneurysms were included. After WEB deployment and before detachment, its distal deployment wire was connected to an EEG receiver, and participants performed a decision-making task for 10 minutes. WEB and scalp recordings were captured.
RESULTS
All patients underwent successful embolization and evEEG with no complications. Event-related potentials were detected on scalp EEG in 9/17 (53%) patients. Of these 9 patients, a task-related low-gamma (30–70 Hz) response on WEB channels was captured in 8/9 (89%) cases. In these 8 patients, the WEB was deployed in 2 middle cerebral arteries, 3 anterior communicating arteries, the terminal internal carotid artery, and 2 basilar tip aneurysms. Electrocardiogram artifact on WEB channels was present in 12/17 cases.
CONCLUSIONS
The WEB implanted within cerebral aneurysms of awake patients is capable of capturing task-specific brain electrical activities. Future studies are warranted to establish the efficacy of and support for evEEG as a tool for brain recording, brain stimulation, and brain-machine interface applications.
Details
- Title: Subtitle
- Intraarterial encephalography from an acutely implanted aneurysm embolization device in awake humans
- Creators
- Luyuan LiKenji IbayashiAnthony PiscopoCarolina Deifelt StreeseHaiming ChenJeremy D W GreenleeDavid M Hasan
- Resource Type
- Journal article
- Publication Details
- Journal of neurosurgery, Vol.138(3), pp.785-792
- DOI
- 10.3171/2022.6.JNS22932
- ISSN
- 0022-3085
- eISSN
- 1933-0693
- Language
- English
- Electronic publication date
- 08/05/2022
- Date published
- 03/2023
- Academic Unit
- Neurosurgery; Roy J. Carver Department of Biomedical Engineering; Iowa Neuroscience Institute; Otolaryngology; Stead Family Department of Pediatrics
- Record Identifier
- 9984296994102771
Metrics
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