Journal article
Intracellular Ca2+ and adaptation of voltage responses to light in Hermissenda photoreceptors
Neuroreport, Vol.9(7), pp.1625-1631
05/11/1998
DOI: 10.1097/00001756-199805110-00067
PMID: 9631477
Abstract
Fluorescent imaging of Ca2+ and intracellular recordings were used to assess Ca2+ increases and voltage responses during light presentations in Hermissenda B photoreceptors. Ca2+ levels increased and were sustained during a relatively long exposure to light. Repeated presentations of a brief light induced an elevation of intracellular Ca2+ that persisted throughout short interlight intervals, but which dissipated during long interlight intervals. In all instances, the magnitude of the intracellular Ca2+ signal was inversely related to the amplitude of the light-induced generator potential. Blocking of voltage-dependent Ca2+ channels did not significantly affect the magnitude of the Ca2+ signal, suggesting that the intracellular Ca2+ response arises primarily from release from intracellular stores. These results indicate that Ca2+ plays an important role in the modulation of the voltage responses to light, acting to suppress the response during repetitive or prolonged stimulation.
Details
- Title: Subtitle
- Intracellular Ca2+ and adaptation of voltage responses to light in Hermissenda photoreceptors
- Creators
- I A Muzzio - Rutgers, The State University of New JerseyA C Talk - Rutgers, The State University of New JerseyL D Matzel - Rutgers, The State University of New Jersey
- Resource Type
- Journal article
- Publication Details
- Neuroreport, Vol.9(7), pp.1625-1631
- DOI
- 10.1097/00001756-199805110-00067
- PMID
- 9631477
- NLM abbreviation
- Neuroreport
- ISSN
- 0959-4965
- eISSN
- 1473-558X
- Grant note
- MH48387 / NIMH NIH HHS
- Language
- English
- Date published
- 05/11/1998
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984295026802771
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