Intracranial aneurysms and subarachnoid hemorrhage --- report on a randomized treatment study. IV-B. Regulated bed rest --- statistical evaluation

W G Henderson; J C Torner; D W Nibbelink

doi:10.1161/01.STR.8.5.579

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Intracranial aneurysms and subarachnoid hemorrhage --- report on a randomized treatment study. IV-B. Regulated bed rest --- statistical evaluation

Journal article

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Intracranial aneurysms and subarachnoid hemorrhage --- report on a randomized treatment study. IV-B. Regulated bed rest --- statistical evaluation

W G Henderson, J C Torner and D W Nibbelink

Stroke (1970), Vol.8(5), pp.579-589

09/1977

DOI: 10.1161/01.STR.8.5.579

PMID: 906058

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Abstract

Regulated bed rest was one of four treatment modalities evaluated in a randomized clinical trial conducted between 1963 and 1970 for patients with a ruptured intracranial aneurysm. A life table method of statistical analysis was used to determine cumulative mortality znd rebleeding rate during a five-year follow-up period for 187 patients in this treatment program and for subgroups of this patient sample. Linear discriminant function analysis was used to develop equations of clinical variables to predict mortality and rebleeding during the 90-day period following the bleed. The clinical variables found to be most indicative of mortality included a poor initial neurological and medical state and sex (male). Other variables somewhat indicative of high mortality but not reaching statistical significance included a short interval from last bleeding to treatment, high mean blood pressure, and a large aneurysm.

Recurrence

Bed Rest

Subarachnoid Hemorrhage - therapy

Humans

Middle Aged

Intracranial Aneurysm - mortality

Male

Intracranial Aneurysm - complications

Intracranial Aneurysm - diagnosis

Intracranial Aneurysm - therapy

Rupture, Spontaneous - complications

Subarachnoid Hemorrhage - etiology

Subarachnoid Hemorrhage - mortality

Adult

Female

Subarachnoid Hemorrhage - diagnosis

Rupture, Spontaneous - therapy

Details

Title: Subtitle: Intracranial aneurysms and subarachnoid hemorrhage --- report on a randomized treatment study. IV-B. Regulated bed rest --- statistical evaluation
Creators: W G Henderson
J C Torner
D W Nibbelink
Resource Type: Journal article
Publication Details: Stroke (1970), Vol.8(5), pp.579-589
DOI: 10.1161/01.STR.8.5.579
PMID: 906058
NLM abbreviation: Stroke
ISSN: 0039-2499
eISSN: 1524-4628
Publisher: United States
Language: English
Date published: 09/1977
Academic Unit: Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
Record Identifier: 9983995119402771

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