Journal article
Intracranial dissemination of an ACTH secreting pituitary neoplasm - a case report and review of the literature
Journal of endocrinological investigation, Vol.15(5), pp.387-391
1992
DOI: 10.1007/BF03348759
PMID: 1324266
Abstract
A 52-year-old woman developed recurrent hypercortisolism 3 yr after successful surgical treatment of Cushing's disease. At postmortem, eosinophilic pituitary tissue showing positive ACTH immunohistochemical staining was present in the frontal lobe and cerebellum but there was no tumor in the sella. In the absence of a pituitary tumor, extrasellar ACTH producing tissue could arise from seeding of the cerebrospinal fluid with tumor cells at the time of operation or from an atypical pituitary carcinoma. In this report we review the mechanisms of intracranial dissemination of pituitary tissue and ACTH-secreting pituitary carcinomas, including parasellar invasion, meningeal seeding, and cerebrospinal and hematogenous spread.
Details
- Title: Subtitle
- Intracranial dissemination of an ACTH secreting pituitary neoplasm - a case report and review of the literature
- Creators
- D TONNER - Univ. Iowa coll. medicine, dep. internal medicine, Iowa City IA, United StatesP BELDING - Univ. Iowa coll. medicine, dep. internal medicine, Iowa City IA, United StatesS. A MOORE - Univ. Iowa coll. medicine, dep. internal medicine, Iowa City IA, United StatesJ. A SCHLECHTE - Univ. Iowa coll. medicine, dep. internal medicine, Iowa City IA, United States
- Resource Type
- Journal article
- Publication Details
- Journal of endocrinological investigation, Vol.15(5), pp.387-391
- Publisher
- Kurtis; Milano
- DOI
- 10.1007/BF03348759
- PMID
- 1324266
- ISSN
- 0391-4097
- eISSN
- 1720-8386
- Language
- English
- Date published
- 1992
- Academic Unit
- Pathology; Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984046817602771
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