Journal article
Intramolecular nucleophilic aromatic substitution reactions of (η 6 -arene)ruthenium complexes: preparation of substituted 2-tetralones
Tetrahedron letters, Vol.42(1), pp.17-20
01/2001
DOI: 10.1016/S0040-4039(00)01885-2
Abstract
A stabilized enolate attached with a carbon tether to a cationic (η6-arene)RuIICp moiety was found to participate in an intramolecular SNAr reaction to deliver Ru-coordinated 1-acetyl-2-tetralone. Nucleophilic aromatic substitutions involving substituted β-dicarbonyl nucleophiles proceeded with concomitant deacetylation to afford 1-alkyl-2-tetralone derivatives. The 2-tetralone products were found to be amenable to further stereocontrolled elaboration via benzylic alkylation. © 2000 Elsevier Science Ltd.
Details
- Title: Subtitle
- Intramolecular nucleophilic aromatic substitution reactions of (η 6 -arene)ruthenium complexes: preparation of substituted 2-tetralones
- Creators
- F.Christopher PiggeShiyue Fang
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.42(1), pp.17-20
- DOI
- 10.1016/S0040-4039(00)01885-2
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 01/2001
- Academic Unit
- Radiology; Chemistry
- Record Identifier
- 9984216715202771
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