Journal article
Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis
The New England Journal of Medicine, Vol.343(13), pp.898-904
09/28/2000
DOI: 10.1056/NEJM200009283431301
PMID: 11006365
Abstract
Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system that most commonly affects women, with an onset typically between 20 and 40 years of age. A diagnosis of clinically definite multiple sclerosis requires the occurrence of at least two neurologic events consistent with demyelination that are separated both anatomically in the central nervous system and temporally. 1 Magnetic resonance imaging (MRI) of the brain, by identifying lesions consistent with the occurrence of demyelination, can add certainty to the diagnosis. 2 , 3 The presence of such MRI-identified lesions in a patient with an isolated syndrome of the optic nerve . . .
Details
- Title: Subtitle
- Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis
- Creators
- Lawrence D JacobsRoy W BeckJack H SimonR. Phillip KinkelCarol M BrownscheidleThomas J MurrayNancy A SimonianPeter J SlasorAlfred W Sandrockthe CHAMPS Study Group
- Contributors
- Michael Wall (Contributor) - University of Iowa, Ophthalmology and Visual Sciences
- Resource Type
- Journal article
- Publication Details
- The New England Journal of Medicine, Vol.343(13), pp.898-904
- DOI
- 10.1056/NEJM200009283431301
- PMID
- 11006365
- NLM abbreviation
- N Engl J Med
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Publisher
- Massachusetts Medical Society
- Language
- English
- Date published
- 09/28/2000
- Academic Unit
- Neurology; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980070802771
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