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Intraocular bevacizumab in the treatment of choroidal metastases from breast cancer
Journal article   Open access   Peer reviewed

Intraocular bevacizumab in the treatment of choroidal metastases from breast cancer

José Pablo Leone and Kalyan Nadiminti
BMJ Case Reports, Vol.2016
07/18/2016
DOI: 10.1136/bcr-2016-215719
PMID: 27435845
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Intraocular bevacizumab in the treatment of choroidal metastases1.29 MBDownloadView
Published (Version of record)CC BY-NC V4.0 Open Access
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https://doi.org/10.1136/bcr-2016-215719View
Published (Version of record)BMJ Case Rep. Published online:18 July 2016.

Abstract

Description: We report the case of a 38-year-old woman who was initially diagnosed with stage II oestrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor receptor 2 (HER2) negative infiltrating ductal carcinoma of the breast, in 2013. Breast MRI at that time showed multifocal disease in the right breast. The patient underwent a right mastectomy and axillary lymph node dissection, which revealed pT2 N1a breast cancer. Following this, she received four cycles of docetaxel and cyclophosphamide and adjuvant radiation. At that time, she had declined tamoxifen due to her history of lattice degeneration and concerns of retinal detachment. She was also offered letrozole with goserelin but declined due to their side effect profile and risk for retinal complications.
Hematology Internal Medicine Oncology Ophthalmology Musculoskeletal, Neural, and Ocular Physiology Obstetrics and Gynecology OAfund Adult Angiogenesis Inhibitors Bevacizumab Breast Neoplasms Choroid Choroid Neoplasms Female Humans Injections Intraocular

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