Journal article
Intravenous dexamethasone does not prolong the duration of pudendal nerve block in infants and children undergoing hypospadias surgery: A randomized clinical trial
Pediatric anesthesia, Vol.34(3), pp.259-266
03/2024
DOI: 10.1111/pan.14805
PMID: 38037830
Abstract
The administration of intravenous dexamethasone increases the duration of neuraxial block and improves the quality of analgesia. However, little is known about these effects of dexamethasone on peripheral nerve blocks in children.
In this study, we aimed to investigate the benefit of intravenous dexamethasone for enhancing the effect of pudendal block on postoperative analgesia in children who underwent hypospadias surgery.
In total, 46 children aged 6-36 months who underwent hypospadias surgery were randomly allocated to either a control group (normal saline, group C) or dexamethasone group (0.5 mg/kg, group D). Pudendal block was performed before the surgery using 0.3 mL/kg of 0.225% ropivacaine on both sides. Parents were instructed to press the patient-controlled analgesia bolus button when their children's pain score was >4 points. The primary outcome measure was the time at which the first patient-controlled analgesia by proxy bolus dose was administered. The secondary outcome measures were pain score, number of patient-controlled analgesia administration by proxy bolus attempts, number of rescue analgesics required, total amount of fentanyl administered, and overall parental satisfaction.
The time of first patient-controlled analgesia bolus administration by proxy was not different between the control and dexamethasone groups (5.6 [5.2, 8.8] h versus 6.5 [5.4, 8.1] h, hazard ratio 0.8, 95% confidence intervals 0.43 to 1.47, p = .46). There were no statistically significant differences among the secondary outcomes.
Administration of intravenous dexamethasone did not enhance the duration of pudendal nerve block in infants and children aged 6-36 months who underwent hypospadias surgery.
Details
- Title: Subtitle
- Intravenous dexamethasone does not prolong the duration of pudendal nerve block in infants and children undergoing hypospadias surgery: A randomized clinical trial
- Creators
- Young-Eun Joe - Yonsei UniversityJae-Hoon Lee - Yonsei UniversityDarhae Eum - Yonsei UniversityJi-Ho Kim - Yonsei UniversityJeong-Rim Lee - Yonsei University
- Resource Type
- Journal article
- Publication Details
- Pediatric anesthesia, Vol.34(3), pp.259-266
- DOI
- 10.1111/pan.14805
- PMID
- 38037830
- ISSN
- 1155-5645
- eISSN
- 1460-9592
- Language
- English
- Date published
- 03/2024
- Academic Unit
- Anesthesia
- Record Identifier
- 9984806604702771
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