Intravenous thrombolytic therapy for patients with ventricular assist device thrombosis: An attempt to avoid reoperation

Beth T Webber; Anthony L Panos; Yiliam F Rodriguez-Blanco

doi:10.4103/0971-9784.173047

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Intravenous thrombolytic therapy for patients with ventricular assist device thrombosis: An attempt to avoid reoperation

Journal article

Open access

Peer reviewed

Intravenous thrombolytic therapy for patients with ventricular assist device thrombosis: An attempt to avoid reoperation

Beth T Webber, Anthony L Panos and Yiliam F Rodriguez-Blanco

Annals of cardiac anaesthesia, Vol.19(1), pp.192-196

2016

DOI: 10.4103/0971-9784.173047

PMCID: PMC4900393

PMID: 26750701

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Abstract

A growing number of patients are undergoing prolonged management of advanced heart failure with the use of continuous flow left ventricular assist devices (LVADs). Subsequently, an increasing number of patients are presenting with complications associated with these devices. Based on an analysis of three major LVAD institutions, the number of patients developing LVAD pump thrombosis may be much higher than originally projected.[ 1 2 ] The management of this highly feared complication continues to be challenging, as the population of LVAD patients is very heterogeneous and heavily burdened with comorbidities. The standard protocol of increasing anticoagulation may fail to achieve successful resolution of thrombus. Difficulty and poor prognosis may make reoperation less than desirable. Here, we present a case of successful thrombolysis following intravenous administration of tissue plasminogen activator in the Intensive Care Unit setting.

Left ventricular assist devices thrombosis

Ventricular assist device

Case Report

Thrombolytic therapy

Details

Title: Subtitle: Intravenous thrombolytic therapy for patients with ventricular assist device thrombosis: An attempt to avoid reoperation
Creators: Beth T Webber - Department of Anesthesia, Division of Cardiovascular Anesthesia, University of Miami, Florida, USA
Anthony L Panos - Department of Cardiovascular Surgery, University of Miami, Florida, USA
Yiliam F Rodriguez-Blanco - Department of Anesthesia, Division of Cardiovascular Anesthesia, University of Miami, Florida, USA
Resource Type: Journal article
Publication Details: Annals of cardiac anaesthesia, Vol.19(1), pp.192-196
DOI: 10.4103/0971-9784.173047
PMID: 26750701
PMCID: PMC4900393
NLM abbreviation: Ann Card Anaesth
ISSN: 0971-9784
eISSN: 0974-5181
Publisher: Medknow Publications & Media Pvt Ltd; India
Language: English
Date published: 2016
Academic Unit: Surgery; Cardiothoracic Surgery
Record Identifier: 9984051785402771

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