Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient

Gina Lockwood; Charles Durkee; Travis Groth

doi:10.1155/2016/4569684

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Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient

Journal article

Open access

Peer reviewed

Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient

Gina Lockwood, Charles Durkee and Travis Groth

Case reports in urology, Vol.2016, pp.4569684-4

2016

DOI: 10.1155/2016/4569684

PMCID: PMC4781947

PMID: 27006855

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Abstract

Introduction . We present a novel case of persistent autonomic dysreflexia in a pediatric spinal cord injury patient treated successfully with intravesical botulinum toxin. Study Design . A retrospective chart review of one patient seen at the Children's Hospital of Wisconsin from 2006 to 2012 was performed. Results . A pediatric spinal cord injury patient with known neurogenic bladder presented with severe hypertension consistent with autonomic dysreflexia. His symptoms and hypertension did not improve with conservative measures, and he necessitated ICU admission and antihypertensive drips. He was taken to the operating room for intravesical botulinum toxin for refractory bladder spasms. Following this, his symptoms abated, and he was weaned off IV antihypertensives and returned to his baseline state. His symptoms were improved for greater than six months. Conclusions . There are few treatment options for the management of refractory autonomic dysreflexia. Intravesical botulinum toxin has never been reported for this use. Dedicated research is warranted to assess its efficacy, as it was used successfully to abort autonomic dysreflexia in this patient.

Case Report

Details

Title: Subtitle: Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient
Creators: Gina Lockwood - Department of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Charles Durkee - Department of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Travis Groth - Department of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Resource Type: Journal article
Publication Details: Case reports in urology, Vol.2016, pp.4569684-4
DOI: 10.1155/2016/4569684
PMID: 27006855
PMCID: PMC4781947
NLM abbreviation: Case Rep Urol
ISSN: 2090-696X
eISSN: 2090-6978
Publisher: Hindawi Publishing Corporation
Language: English
Date published: 2016
Academic Unit: Stead Family Department of Pediatrics; Urology
Record Identifier: 9984051522802771

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