Journal article
Investigation of a noninvasive detector system for quantitative [O-15]water blood flow studies in PET
IEEE transactions on nuclear science, Vol.48(1), pp.31-37
02/2001
DOI: 10.1109/23.910829
Abstract
The investigation of human cerebral function has been one of the most challenging subjects in the last century. Imaging studies that use positron emission tomography (PET) with [O-15]water have been central for the assessment of neurophysiological activity. Accurate and quantitative estimation of regional cerebral blood flow (rCBF) for mapping of brain function requires measurement of the post-injection arterial time course of [O-15]water. The overall purpose of this work is to design and build a small inexpensive tomograph that can be placed around a subject's neck or wrist to noninvasively measure the arterial radioactivity input function. Monte Carlo simulations and experimental investigations have been performed to assist in defining the design characteristics of the detectors to be used for this system.
Details
- Title: Subtitle
- Investigation of a noninvasive detector system for quantitative [O-15]water blood flow studies in PET
- Creators
- M Aykac - Dept. of Phys. & Astron., Iowa Univ., Iowa City, IA, USAR.D HichwaG.L Watkins
- Resource Type
- Journal article
- Publication Details
- IEEE transactions on nuclear science, Vol.48(1), pp.31-37
- Publisher
- IEEE
- DOI
- 10.1109/23.910829
- ISSN
- 0018-9499
- eISSN
- 1558-1578
- Language
- English
- Date published
- 02/2001
- Academic Unit
- Radiology; Research Administration; Physics and Astronomy; Radiation Oncology
- Record Identifier
- 9984213444502771
Metrics
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