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Investigational Antifungal Agents
Journal article   Open access   Peer reviewed

Investigational Antifungal Agents

Erika J. Ernst
Pharmacotherapy, Vol.21(8P2), pp.165S-174S
08/2001
DOI: 10.1592/phco.21.12.165S.34509
PMID: 11501989
url
https://doi.org/10.1592/phco.21.12.165S.34509View
Published (Version of record) Open Access

Abstract

Several new antifungal agents, including novel compounds in familiar classes and entirely new classes targeting previously untapped mechanisms, are in various stages of the drug development process. Many new triazole antifungal agents are being studied, including voriconazole, posaconazole, and ravuconazole. The echinocandin antifungals, which represent a new class of antifungal agents, possess activity against a variety of fungal pathogens. The sodarin derivatives and nikkomycins are two additional classes of antifungals in early stages of development; future studies will determine their therapeutic usefulness.

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