Investing in prospective cohorts for etiologic study of occupational exposures

A Blair; C J Hines; K W Thomas; M C R Alavanja; L. E. Beane Freeman; J A Hoppin; F Kamel; C F Lynch; J H Lubin; D T Silverman; E Whelan; S H Zahm; D P Sandler

doi:10.1002/ajim.22403

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Investing in prospective cohorts for etiologic study of occupational exposures

Journal article

Peer reviewed

Investing in prospective cohorts for etiologic study of occupational exposures

A Blair, C J Hines, K W Thomas, M C R Alavanja, L. E. Beane Freeman, J A Hoppin, F Kamel, C F Lynch, J H Lubin, D T Silverman, …

American journal of industrial medicine, Vol.58(2), pp.113-122

02/2015

DOI: 10.1002/ajim.22403

PMCID: PMC4516175

PMID: 25603935

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Abstract

Prospective cohorts have played a major role in understanding the contribution of diet, physical activity, medical conditions, and genes to the development of many diseases, but have not been widely used for occupational exposures. Studies in agriculture are an exception. We draw upon our experience using this design to study agricultural workers to identify conditions that might foster use of prospective cohorts to study other occupational settings. Prospective cohort studies are perceived by many as the strongest epidemiologic design. It allows updating of information on exposure and other factors, collection of biologic samples before disease diagnosis for biomarker studies, assessment of effect modification by genes, lifestyle, and other occupational exposures, and evaluation of a wide range of health outcomes. Increased use of prospective cohorts would be beneficial in identifying hazardous exposures in the workplace. Occupational epidemiologists should seek opportunities to initiate prospective cohorts to investigate high priority, occupational exposures.

Epidemiologic Research Design

Occupational Medicine

Prospective Studies

Occupational Exposure - analysis

Agricultural Workers' Diseases - etiology

Humans

Details

Title: Subtitle: Investing in prospective cohorts for etiologic study of occupational exposures
Creators: A Blair - Division of Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland
C J Hines
K W Thomas
M C R Alavanja
L. E. Beane Freeman
J A Hoppin
F Kamel
C F Lynch
J H Lubin
D T Silverman
E Whelan
S H Zahm
D P Sandler
Resource Type: Journal article
Publication Details: American journal of industrial medicine, Vol.58(2), pp.113-122
DOI: 10.1002/ajim.22403
PMID: 25603935
PMCID: PMC4516175
NLM abbreviation: Am J Ind Med
ISSN: 0271-3586
eISSN: 1097-0274
Publisher: Wiley; United States
Grant note: CC999999 / Intramural CDC HHS Intramural NIH HHS
Language: English
Date published: 02/2015
Academic Unit: Epidemiology
Record Identifier: 9983995146202771

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