Journal article
Iowa Newborn Screening Program Experience with Hemoglobinopathy Screening over the Last Two Decades and Its Increasing Global Relevance
International journal of neonatal screening, Vol.10(1), 21
03/08/2024
DOI: 10.3390/ijns10010021
PMCID: PMC10971335
PMID: 38535125
Abstract
Hemoglobinopathies are the commonest monogenic disorder worldwide, with approximately seven percent of the world population being carriers of hemoglobinopathies. The healthcare utilization impact of thalassemia has resulted in global public health initiatives to screen for hemoglobinopathies, especially sickle cell disease (SCD). The Iowa Newborn Screening Program (INSP) has been in place for more than 50 years with a primary focus on detecting SCD. Recent changes in migration patterns have led to a global distribution of hemoglobinopathies in the western world, which has translated to an increase in the diagnosis of SCD and the incidental detection of non-sickling hemoglobinopathies within the INSP. This study documents the birth prevalence of hemoglobinopathies diagnosed in newborns through the INSP and highlights the need for newborn screening programs to evolve to meet the healthcare needs of underserved, minority populations.
Details
- Title: Subtitle
- Iowa Newborn Screening Program Experience with Hemoglobinopathy Screening over the Last Two Decades and Its Increasing Global Relevance
- Creators
- Ryan Jilek - University of IowaJennifer Marcy - University of IowaCarol Johnson - University of IowaGeorgianne Younger - University of IowaAmy Calhoun - University of IowaMoon Ley Tung - University of Iowa
- Resource Type
- Journal article
- Publication Details
- International journal of neonatal screening, Vol.10(1), 21
- DOI
- 10.3390/ijns10010021
- PMID
- 38535125
- PMCID
- PMC10971335
- eISSN
- 2409-515X
- Language
- English
- Date published
- 03/08/2024
- Academic Unit
- Stead Family Department of Pediatrics; Medical Genetics and Genomics
- Record Identifier
- 9984577113402771
Metrics
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