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Ipsilateral retinopetal projection of the nucleus olfactoretinalis (NOR) during development and regeneration: a DiI study in a cichlid fish
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Ipsilateral retinopetal projection of the nucleus olfactoretinalis (NOR) during development and regeneration: a DiI study in a cichlid fish

C Wilm and B Fritzsch
Journal of neurobiology, Vol.24(1), pp.70-79
01/1993
DOI: 10.1002/neu.480240106
PMID: 8419524

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Abstract

The development and regeneration of the ipsilateral retinopetal projection of the nucleus olfactoretinalis (NOR) in the cichlid fish Haplochromis burtoni was studied with 1,1'-dioctadecyl-3,3,3',3'-tetramethyl indocarbocyanine perchlorate (DiI) in fixed tissue. Throughout development most NOR cells projected to the contralateral retina. Only an insignificant, transient elevation of a projection to the ipsilateral retina was found in a few animals; however, after severing the contralateral processes of NOR cells by either enucleation or nerve crush, many animals had significantly more NOR cells with a regenerated process to the ipsilateral retina. Nevertheless, within a few weeks of surgery, the number of animals with ipsilaterally projecting cells were reduced to control values. The transiently enhanced ipsilateral projections to the retina imply changes in the guiding mechanism after these operations and the existence of control mechanisms against unusual connections to the retina in this bony fish.
Retina - growth & development Eye Enucleation Nerve Regeneration - physiology Neural Pathways - growth & development Nerve Crush Neural Pathways - physiology Perches - physiology Carbocyanines Retina - physiology Olfactory Pathways - physiology Animals Perches - growth & development Olfactory Pathways - growth & development Fluorescent Dyes

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