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Is There a Link Between Fluoridated Water and Osteosarcoma?
Journal article   Peer reviewed

Is There a Link Between Fluoridated Water and Osteosarcoma?

Sheila M McGuire, Eleanor D Vanable, Michael H McGuire, Joseph A Buckwalter and Chester W Douglass
The Journal of the American Dental Association (1939), Vol.122(4), pp.38-45
04/1991
DOI: 10.14219/jada.archive.1991.0149
PMID: 2022786

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Abstract

This study by Dr. Sheila McGuire and others not only refutes a link between fluoride ingestion and osteosarcoma formation, but also suggests that fluoride may protect against this cancer. To test the hypothesis that fluoride is a risk factor for osteosarcoma, a case control study compared the complete residential fluoride histories of osteosarcoma patients with matched hospital-based controls. Fluoridation was not found to be a risk factor for osteosarcoma in the study population. The trend in the data from this small sample study suggests the hypothesis that a protective effect may exist against the formation of osteosarcoma for individuals consuming fluoridated water.

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