Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis? [version 1; peer review: 2 approved]

Andrew Levy; Nabeel Hamzeh; Lisa A Maier

doi:10.12688/f1000research.11068.1

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Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis? [version 1; peer review: 2 approved]

Journal article

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Peer reviewed

Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis? [version 1; peer review: 2 approved]

Andrew Levy, Nabeel Hamzeh and Lisa A Maier

F1000 research, Vol.7, p.600

2018

DOI: 10.12688/f1000research.11068.1

PMCID: PMC5958314

PMID: 29946423

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Abstract

In this review, we argue for the use of high-resolution computed tomography (HRCT) over chest X-ray in the initial evaluation of patients with sarcoidosis. Chest X-ray, which has long been used to classify disease severity and offer prognostication in sarcoidosis, has clear limitations compared with HRCT, including wider interobserver variability, a looser association with lung function, and poorer sensitivity to detect important lung manifestations of sarcoidosis. In addition, HRCT offers a diagnostic advantage, as it better depicts targets for biopsy, such as mediastinal/hilar lymphadenopathy and focal parenchymal disease. Newer data suggest that specific HRCT findings may be associated with important prognostic outcomes, such as increased mortality. As we elaborate in this update, we strongly recommend the use of HRCT in the initial evaluation of the patient with sarcoidosis.

diagnosis

sarcoidosis

chest X-ray

high-resolution computed tomography

Details

Title: Subtitle: Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis? [version 1; peer review: 2 approved]
Creators: Andrew Levy - Division of Pulmonary and Critical Care Sciences, Department of Medicine, University of Colorado School of Medicine, Denver, CO, USA
Nabeel Hamzeh - Division of Pulmonary and Critical Care Sciences, Department of Medicine, University of Colorado School of Medicine, Denver, CO, USA
Lisa A Maier - Environmental and Occupational Health Department, Colorado School of Public Health, University of Colorado, Denver, CO, USA
Resource Type: Journal article
Publication Details: F1000 research, Vol.7, p.600
DOI: 10.12688/f1000research.11068.1
PMID: 29946423
PMCID: PMC5958314
NLM abbreviation: F1000Res
ISSN: 2046-1402
eISSN: 2046-1402
Language: English
Date published: 2018
Academic Unit: Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
Record Identifier: 9984094569002771

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