Journal article
Is the Neutrophil-to-Lymphocyte Ratio Associated With Increased Morbidity After Colorectal Surgery?
Surgical laparoscopy, endoscopy & percutaneous techniques, Vol.29(1), pp.36-39
02/01/2019
DOI: 10.1097/SLE.0000000000000588
PMID: 30358649
Abstract
Purpose: We aimed to evaluate the association between preoperative and postoperative neutrophil-to-lymphocyte ratio (NLR) and 30-day postoperative complications after colorectal surgery. Methods: Patients undergoing elective colorectal surgery between January, 2010 and December, 2014 were identified. Patients who had preoperative and postoperative days 1 and 2 (Postoperative day [POD]-1, POD-2) NLR were included in the study. Primary study outcomes were optimal NLR cutoff values at preop, POD-1, and POD-2. Results: A total of 1328 patients met the inclusion criteria. Of those, 518 (39%) patients experienced at least one postoperative complication. Sex (P<0.001), diabetes mellitus (DM) (P<0.001), diagnosis (P=0.001), operation type (P=0.03), and open surgery (P<0.001) were statistically associated with higher NLR (POD-1, P=0.02; POD2, P=0.01). DM (OR, 1.97; 95%CI, 1.27-3.08; P=0.003] and NLR on POD-2 >= 9.2 (OR, 1.43; 95%CI, 1.03-1.98; P=0.02) were significantly related to postoperative complications. Conclusions: NLR may provide clinicians with an additional tool for identifying patients at high risk for postoperative complications after elective colorectal surgery. Routine use of NLR may lead to early intervention and potentially improve the management of complications after colorectal surgery.
Details
- Title: Subtitle
- Is the Neutrophil-to-Lymphocyte Ratio Associated With Increased Morbidity After Colorectal Surgery?
- Creators
- Cigdem Benlice - Cleveland Clin, Digest Dis & Surg Inst, Dept Gen Surg, Cleveland, OH 44106 USAAkin Onder - Cleveland ClinicRovnat Babazade - The University of Texas Medical Branch at GalvestonJennifer Hrabe - Cleveland ClinicLuca Stocchi - Cleveland ClinicScott Steele - Cleveland ClinicEmre Gorgun - Cleveland Clinic
- Resource Type
- Journal article
- Publication Details
- Surgical laparoscopy, endoscopy & percutaneous techniques, Vol.29(1), pp.36-39
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/SLE.0000000000000588
- PMID
- 30358649
- ISSN
- 1530-4515
- eISSN
- 1534-4908
- Number of pages
- 4
- Language
- English
- Date published
- 02/01/2019
- Academic Unit
- Surgery
- Record Identifier
- 9984544950902771
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