Is there a difference in the oral health status of healthy patients and those with inherited bleeding disorders? A systematic review and meta-analysis of case-control studies

Mateus de Azevedo Kinalski; Lucas Peixoto de Araujo; Mateus Bertolini Fernandes dos Santos

doi:10.1016/j.dentre.2022.100046

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Is there a difference in the oral health status of healthy patients and those with inherited bleeding disorders? A systematic review and meta-analysis of case-control studies

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Is there a difference in the oral health status of healthy patients and those with inherited bleeding disorders? A systematic review and meta-analysis of case-control studies

Mateus de Azevedo Kinalski, Lucas Peixoto de Araujo and Mateus Bertolini Fernandes dos Santos

Dentistry Review, Vol.2(2), 100046

06/2022

DOI: 10.1016/j.dentre.2022.100046

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Abstract

The aim of this systematic review and meta-analysis of case-control studies was to identify the differences in oral health status between inherited bleeding disorders (IBDs) and healthy patients. Only case-control studies were included in this review. The risk of bias was assessed using the NOS tool. The random-effects meta-analysis was performed for DMFT and Oral Health Index outcomes. Online databases were searched to identify studies reporting a comparison between IBDs oral health conditions (DMFT, Oral Health Index) and healthy patients. Eight case-control studies were included. The majority of the included studies presented a high degree of methodological quality, while one presented a high risk of bias. A meta-analysis regarding the mean DMFT between IBDs and healthy patients reported that children and teenagers (p = 0.52; I² = 73%) or adult patients (p = 0.96, I²= 0) did not present statistically significant differences compared to control groups. The overall DMFT mean difference between IBDs and healthy patients was -0.18 (p = 0.64, I²=0). There are no differences considering the caries experience of inherited bleeding disorders compared to healthy patients. The available evidence indicates that patients with inherited bleeding disorders present similar caries experience with healthy subjects.

caries

case-control

DMFT

inherited bleeding disorders

meta-analysis

Details

Title: Subtitle: Is there a difference in the oral health status of healthy patients and those with inherited bleeding disorders? A systematic review and meta-analysis of case-control studies
Creators: Mateus de Azevedo Kinalski - Faculty of Dentistry, Community University of Chapecó Region, Federal University of Pelotas, 457 Gonçalves Chaves street, room 502, Chapecó, SC 96015-560, Brazil
Lucas Peixoto de Araujo - Universidade Estadual de Campinas (UNICAMP)
Mateus Bertolini Fernandes dos Santos - Universidade Federal de Pelotas
Resource Type: Journal article
Publication Details: Dentistry Review, Vol.2(2), 100046
DOI: 10.1016/j.dentre.2022.100046
ISSN: 2772-5596
eISSN: 2772-5596
Publisher: Elsevier Inc
Language: English
Date published: 06/2022
Academic Unit: Prosthodontics
Record Identifier: 9984945909902771

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