Journal article
Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI
Journal of magnetic resonance (1997), Vol.165(2), pp.309-314
2003
DOI: 10.1016/j.jmr.2003.08.007
PMID: 14643714
Abstract
Intermolecular multiple-quantum coherence (iMQC) MR imaging provides a fundamentally different contrast mechanism. It allows probing tissue microstructure by tuning the direction and strength of the correlation gradient. However, iMQC images of a specific quantum-coherence can easily be contaminated by leakage signals from undesired quantum coherences (zero, single, and triple quantum coherence in this work). Using a modified double-quantum CRAZED imaging sequence, we show that signals originating from various coherence orders (
M=0, 1, 2, 3) can be predicted in
k-space and effectively isolated by means of a four-step phase cycling scheme and judicious choice of flip angles. Finally, preliminary data suggest the method to be able to provide information on trabecular bone architecture such as regional mean trabecular plate separation.
Details
- Title: Subtitle
- Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI
- Creators
- Chih-Liang Chin - Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104-4283, USAXiaoping Tang - Department of Chemistry, Princeton University, Princeton, NJ, USALouis-S Bouchard - Department of Chemistry, Princeton University, Princeton, NJ, USAPunam K Saha - Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104-4283, USAWarren S Warren - Department of Chemistry, Princeton University, Princeton, NJ, USAFelix W Wehrli - Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104-4283, USA
- Resource Type
- Journal article
- Publication Details
- Journal of magnetic resonance (1997), Vol.165(2), pp.309-314
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.jmr.2003.08.007
- PMID
- 14643714
- ISSN
- 1090-7807
- eISSN
- 1096-0856
- Language
- English
- Date published
- 2003
- Academic Unit
- Radiology; Electrical and Computer Engineering
- Record Identifier
- 9984051993102771
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