Journal article
Isolation, tactile startle and resting blood pressure in Long-Evans rats
Physiology & behavior, Vol.43(5), pp.609-616
1988
DOI: 10.1016/0031-9384(88)90215-6
PMID: 3200916
Abstract
The effect of social isolation, consisting of individual housing in the vivarium under standard conditions and imposed on male rats older than 90 days, was assessed on tactile startle reactivity, nociception, resting heart rate and arterial blood pressure, and on intercorrelations among these variables. Tactile startle was affected by stimulus intensity, repeated trials and time of testing relative to the light/dark cycle, but not by social isolation from 1 to 29 days. Hot-plate latency was not affected by individual housing from 12 to 43 days. Blood pressure and heart rate were negatively correlated with isolation from 9 to 58 days, showing a significant decline over increasing days of isolation. Although not affected directly by isolation, tactile startle was affected secondarily by differences in blood pressure produced by individual housing. Rats with lower resting pressures responded to low-intensity startle stimuli that were not effective in rats with higher pressures, indicating a threshold difference and suggesting the hypothesis that blood pressure acts to modulate sensory reactivity.
Details
- Title: Subtitle
- Isolation, tactile startle and resting blood pressure in Long-Evans rats
- Creators
- Carrol H Woodworth - Department of Psychology and The Cardiovascular Center, The University of Iowa USAAlan Kim Johnson - Department of Psychology and The Cardiovascular Center, The University of Iowa USA
- Resource Type
- Journal article
- Publication Details
- Physiology & behavior, Vol.43(5), pp.609-616
- DOI
- 10.1016/0031-9384(88)90215-6
- PMID
- 3200916
- NLM abbreviation
- Physiol Behav
- ISSN
- 0031-9384
- eISSN
- 1873-507X
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1988
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health, Sport, and Human Physiology
- Record Identifier
- 9984214756902771
Metrics
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