Journal article
John Cunningham Virus Antibody and Viremia as Predictors of Progressive Multifocal Leukoencephalopathy in Human Immunodeficiency Virus-1-Infected Individuals
Clinical infectious diseases, Vol.53(7), pp.711-715
10/01/2011
DOI: 10.1093/cid/cir507
PMCID: PMC3166351
PMID: 21852452
Abstract
We examined whether prediagnostic John Cunningham virus (JCV) antibodies and viremia are predictors of progressive multifocal leukoencephalopathy (PML) in 83 PML cases and 240 human immunodeficiency virus (HIV) disease-matched controls. JCV viremia was not predictive of PML, but some patients showed higher anti-JCV immunoglobulin G (IgG) responses 6 months prior to diagnosis.
Details
- Title: Subtitle
- John Cunningham Virus Antibody and Viremia as Predictors of Progressive Multifocal Leukoencephalopathy in Human Immunodeficiency Virus-1-Infected Individuals
- Creators
- Raphael P. Viscidi - Johns Hopkins MedicineNina Khanna - University of BaselChen S. Tan - Beth Israel Deaconess Medical CenterXiuhung Li - Johns Hopkins UniversityLisa Jacobson - Johns Hopkins UniversityDavid B. Clifford - Washington University in St. LouisAvindra Nath - Johns Hopkins MedicineJoseph B. Margolick - Johns Hopkins UniversityKeerti V. Shah - Johns Hopkins UniversityHans H. Hirsch - University of BaselIgor J. Koralnik - Beth Israel Deaconess Medical Center
- Resource Type
- Journal article
- Publication Details
- Clinical infectious diseases, Vol.53(7), pp.711-715
- Publisher
- Oxford Univ Press
- DOI
- 10.1093/cid/cir507
- PMID
- 21852452
- PMCID
- PMC3166351
- ISSN
- 1058-4838
- eISSN
- 1537-6591
- Number of pages
- 5
- Grant note
- M01RR000052 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) R01NS047029 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) U01 AI035043; U01 AI035042; T32 AI007061; UO1-AI-35043; UO1-AI-35042; UO1-AI-35040; P30 AI060354; UO1-AI-35041; U01 AI035039; U01 AI035041; UO1-AI-35039; U01 AI035040 / NIAID NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) K24 NS 060950; R01 NS 041198; NS 047029; U01 NS322228; K24 NS060950; K08 NS064215; R01 NS041198; R01 NS047029 / NINDS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) U01AI035039 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) M01 RR000052; 5-MO1-RR-00052 / NCRR NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) P30MH075673 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) P30 MH075673; 5P30MH075673 / NIMH NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
- Language
- English
- Date published
- 10/01/2011
- Academic Unit
- Iowa Neuroscience Institute; Internal Medicine
- Record Identifier
- 9984366289102771
Metrics
10 Record Views