Journal article
Joint contact stresses calculated for acetabular dysplasia patients using discrete element analysis are significantly influenced by the applied gait pattern
Journal of biomechanics, Vol.79, pp.45-53
10/05/2018
DOI: 10.1016/j.jbiomech.2018.07.036
PMCID: PMC6237088
PMID: 30104055
Abstract
Gait modifications in acetabular dysplasia patients may influence cartilage contact stress patterns within the hip joint, with serious implications for clinical outcomes and the risk of developing osteoarthritis. The objective of this study was to understand how the gait pattern used to load computational models of dysplastic hips influences computed joint mechanics. Three-dimensional pre- and post-operative hip models of thirty patients previously treated for hip dysplasia with periacetabular osteotomy (PAO) were developed for performing discrete element analysis (DEA). Using DEA, contact stress patterns were calculated for each pre- and post-operative hip model when loaded with an instrumented total hip, a dysplastic, a matched control, and a normal gait pattern. DEA models loaded with the dysplastic and matched control gait patterns had significantly higher (p = 0.012 and p < 0.001) average pre-operative maximum contact stress than models loaded with the normal gait. Models loaded with the dysplastic and matched control gait patterns had nearly significantly higher (p = 0.051) and significantly higher (p = 0.008) average pre-operative contact stress, respectively, than models loaded with the instrumented hip gait. Following PAO, the average maximum contact stress for DEA models loaded with the dysplastic and matched control patterns decreased, which was significantly different (p < 0.001) from observed increases in maximum contact stress calculated when utilizing the instrumented hip and normal gait patterns. The correlation between change in DEA-computed maximum contact stress and the change in radiographic measurements of lateral center-edge angle were greatest (R2 = 0.330) when utilizing the dysplastic gait pattern. These results indicate that utilizing a dysplastic gait pattern to load DEA models may be a crucial element to capturing contact stress patterns most representative of this patient population.
Details
- Title: Subtitle
- Joint contact stresses calculated for acetabular dysplasia patients using discrete element analysis are significantly influenced by the applied gait pattern
- Creators
- Holly D Thomas-Aitken - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, USAMichael C Willey - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, USAJessica E Goetz - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of biomechanics, Vol.79, pp.45-53
- DOI
- 10.1016/j.jbiomech.2018.07.036
- PMID
- 30104055
- PMCID
- PMC6237088
- NLM abbreviation
- J Biomech
- ISSN
- 0021-9290
- eISSN
- 1873-2380
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 10/05/2018
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Injury Prevention Research Center
- Record Identifier
- 9984040001302771
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