Journal article
Kidney and Pancreas Transplantation in the United States, 1999-2008: The Changing Face of Living Donation
American journal of transplantation, Vol.10(4), pp.987-1002
01/01/2010
DOI: 10.1111/j.1600-6143.2010.03022.x
PMID: 20420648
Abstract
The waiting list for kidney transplantation continued to grow between 1999 and 2008, from 41 177 to 76 089 candidates. However, active candidates represented the minority of this increase (36 951-50 624, a 37% change), while inactive candidates increased over 500% (4226-25 465). There were 5966 living donor (LD) and 10 551 deceased donor (DD) kidney transplants performed in 2008. The total number of pancreas transplants peaked at 1484 in 2004 and has declined to 1273. Although the number of LD transplants increased by 26% from 1999 to 2008, the total number peaked in 2004 at 6647 before declining 10% by 2008. The rate of LD transplantation continues to vary significantly as a function of demographic and geographic factors, including waiting time for DD transplant. Posttransplant survival remains excellent, and there appears to be greater use of induction agents and reduced use of corticosteroids in LD recipients. Significant changes occurred in the pediatric population, with a dramatic reduction in the use of LD organs after passage of the Share 35 rule. Many strategies have been adopted to reverse the decline in LD transplant rates for all age groups, including expansion of kidney paired donation, adoption of laparoscopic donor nephrectomy and use of incompatible LD
Details
- Title: Subtitle
- Kidney and Pancreas Transplantation in the United States, 1999-2008: The Changing Face of Living Donation
- Creators
- D. A. Axelrod - Dartmouth CollegeK. P. McCullough - Arbor Research Collaborative for HealthE. D. Brewer - Baylor College of MedicineB. N. Becker - University of Wisconsin–MadisonD. L. Segev - Johns Hopkins UniversityP. S. Rao - University of Michigan
- Resource Type
- Journal article
- Publication Details
- American journal of transplantation, Vol.10(4), pp.987-1002
- DOI
- 10.1111/j.1600-6143.2010.03022.x
- PMID
- 20420648
- NLM abbreviation
- Am J Transplant
- ISSN
- 1600-6135
- eISSN
- 1600-6143
- Publisher
- Wiley
- Number of pages
- 16
- Grant note
- US Department of Health and Human Services 234-2005-37009C / Health Resources and Services Administration; United States Department of Health & Human Services; United States Health Resources & Service Administration (HRSA)
- Language
- English
- Date published
- 01/01/2010
- Academic Unit
- Surgery
- Record Identifier
- 9984322947602771
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