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Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in the intensive care unit: a real challenge to physicians, scientific community, and society
Journal article

Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in the intensive care unit: a real challenge to physicians, scientific community, and society

Cecilia Godoy Carvalhaes, Rodrigo Cayô and Ana Cristina Gales
Shock (Augusta, Ga.), Vol.39 Suppl 1(7), pp.32-37
05/2013
DOI: 10.1097/SHK.0b013e31828faf1f
PMID: 23481500

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Abstract

The prevalence of multidrug-resistant pathogens, especially in intensive care units, has increased and represents a great concern for medical and scientific community. Infections caused by these pathogens are associated with increased costs, length of hospitalization, and morbidity/mortality rates. The last decade was marked by the spread of carbapenem resistance determinants especially in Enterobacteriaceae isolates. In this review, the Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae is used as an example to discuss the difficulties in dealing with multidrug-resistant pathogens in the intensive care unit setting and how they represent a challenge to the medical-scientific community and, ultimately, the whole society.
Anti-Bacterial Agents - therapeutic use Bacterial Proteins - metabolism beta-Lactamases - metabolism Drug Resistance, Multiple, Bacterial Humans Intensive Care Units Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - enzymology Microbial Sensitivity Tests

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