Journal article
LASER TISSUE SOLDERING FOR HYPOSPADIAS REPAIR:: RESULTS OF A CONTROLLED PROSPECTIVE CLINICAL TRIAL
The Journal of urology, Vol.165(2), pp.574-577
02/2001
DOI: 10.1097/00005392-200102000-00073
PMID: 11176439
Abstract
Purpose: Laser tissue soldering has been shown to provide safe and effective tissue closure by creating an immediate leak-free anastomosis with minimal scar formation. We compared the results of laser tissue soldering and conventional suturing for hyposadias repair. Materials and Methods: A consecutive group of 138 boys 4 months to 8 years old (mean age 15 months) was divided into a standard suturing (84) and a sutureless laser (54) hypospadias repair group. Urethral repair was defined as simple (Thiersch-Duplay or Snodgrass) and complex (onlay island flap or tube) in 101 and 37 cases, respectively. Laser tissue soldering was performed with 50% human albumin solder doped with 2.5 mg./ml. indocyanine green dye using an 808 nm. diode laser at 0.5 W. In the laser group sutures were used for tissue alignment only. At surgery neourethral and penile length, operative time for neourethral construction and the number of sutures or throws were measured. Postoperatively patients were examined for complications of wound healing, stricture or fistula. Results: Mean patient age, urethral defect severity, type of repair, neourethral length anti stenting time plus or minus standard error of mean were not significantly different in the 2 groups. Mean operative time was a fifth as long for laser tissue soldering in simple and complex hypospadias repair compared to controls (1.5 ± 0.1 and 5.1 ± 0.3 versus 8.5 ± 0.8 and 26.7 ± 1.7 minutes, respectively, p <0.001). The mean number of sutures used for tissue alignment in the laser group for simple and complex repair was significantly less than in controls (3.0 ± 0.2 and 8.2 ± 0.6 versus 8.5 ± 0.8 and 23.2 ± 1.5, respectively, p <0.001). All patients were followed a mean of 12 months (minimum 6, maximum 22). The complication rate was 4.7% in the laser group and 10.7% in controls with fistula in 2 of 54 cases, and fistula and meatal stenosis in 7 and 2 of 84, respectively. Conclusions: These preliminary results indicate that laser tissue soldering for hypospadias repair may be performed in almost sutureless fashion and more rapidly than conventional suturing. The ease of the laser technique and the lower complication rate in the laser group indicate that laser tissue soldering is an acceptable means of tissue closure in hypospadias repair.
Details
- Title: Subtitle
- LASER TISSUE SOLDERING FOR HYPOSPADIAS REPAIR:: RESULTS OF A CONTROLLED PROSPECTIVE CLINICAL TRIAL
- Creators
- ANDREW J. Kirsch - University of IowaCHRISTOPHER S. Cooper - University of IowaJOHN Gatti - University of Iowa Hospitals and ClinicsHAL C. Scherz - University of Iowa Hospitals and ClinicsDOUGLAS A. Canning - University of Iowa Hospitals and ClinicsSTEPHEN A. Zderic - University of Iowa Hospitals and ClinicsHOWARD M. Snyder - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.165(2), pp.574-577
- DOI
- 10.1097/00005392-200102000-00073
- PMID
- 11176439
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Language
- English
- Date published
- 02/2001
- Academic Unit
- Stead Family Department of Pediatrics; Urology; Medicine Administration
- Record Identifier
- 9984319991702771
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