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LRP1B functions as a receptor for Pseudomonas exotoxin
Journal article   Peer reviewed

LRP1B functions as a receptor for Pseudomonas exotoxin

Diana V. Pastrana, Alison J. Hanson, Jane Knisely, Guojun Bu and David J. FitzGerald
Biochimica et biophysica acta. Molecular basis of disease, Vol.1741(3), pp.234-239
09/25/2005
DOI: 10.1016/j.bbadis.2005.06.007
PMID: 16095885

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Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors, among them Pseudomonas Exotoxin A (PE). Previously, low-density lipoprotein receptor-related protein 1 (LRP1) was shown to be the primary receptor for PE. In this report, we show that a close family member, LRP1B, can also function as a receptor.
ADP-ribosylation LRP1 LRP1B Pseudomonas Receptor Toxin

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