Journal article
Lambert–Eaton myasthenic syndrome with prominent postexercise exhaustion
Muscle & nerve, Vol.16(7), pp.716-719
07/1993
DOI: 10.1002/mus.880160705
PMID: 8389419
Abstract
A 66‐year‐old man with Lambert–Eaton myasthenic syndrome, polyneuropathy, and small cell lung cancer, developed profound muscle weakness with a prolonged period of ventilatory dependency. Electrophysiological studies demonstrated very small compound muscle action potentials in response to supramaximal nerve stimulation, limited tetanic and postexercise facilitation, and prolonged prominent postexercise exhaustion (40–60% of baseline value) persisting up to 20 minutes. It is hypothesized that these changes may reflect both a severe defect in acetylcholine release and decreased availability of releasible acetylcholine from the terminal axon.
Details
- Title: Subtitle
- Lambert–Eaton myasthenic syndrome with prominent postexercise exhaustion
- Creators
- Ludwig GutmannDavid WeidmanAlvaro Gutierrez
- Resource Type
- Journal article
- Publication Details
- Muscle & nerve, Vol.16(7), pp.716-719
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- DOI
- 10.1002/mus.880160705
- PMID
- 8389419
- ISSN
- 0148-639X
- eISSN
- 1097-4598
- Number of pages
- 4
- Language
- English
- Date published
- 07/1993
- Academic Unit
- Neurology
- Record Identifier
- 9984014023302771
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